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Sept 2017 case month answer

Diagnosis

Liver Angiosarcoma

 

Discussion

Angiosarcoma is a rare tumor but correspond to 2% of liver tumors in adults. It is related with exposure to androgen, steroids, arsenic, thorotrast, vinyl chloride. 

Rares cases are related to previous chemotherapy or radiotherapy, hemochromatosis, estrogen or exposure to other metals. 

The prognosis is very poor with most cases dying within 6 months with frequent lung metastasis. 

Tumors are common multiple and multicentric.  Microscopically, tumor shows multiple infiltrative ansastomosing channelts with mild atypia, CD31+ and HHV8 negative.